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February 7, 2012

Dr. Kather’s Breast Health supplement list

Filed under: Breast shape,Olympia Physician — gary @ 12:31 am

Breast health greatly interests me because my aunt died at 56 years-old from metastatic breast cancer. My goal for all of my clients, family, friends and myself is that we make choices that promote breast health instead of ever having to fight cancer. Smart choices begin with our diet. We want to eat lots of colorful organic vegetables and include essential fatty acids in our diet. A diet high in saturated fats and sugar PROMOTE the risk for cancer, so the standard American diet has created an overwhelming stress on the cancer treatment industry.

NO gifts of candy, cakes, cookies or other sugar-laded items to our clinic please! These items are not “goodies,” but rather bad stress to a person’s health. Celebrate holidays with colorful vegatables and fruits, instead of illness-promoting sugar.

I personally prefer a beautiful Birthday Papaya to a birthday cake. Also, instead of wedding cake, please consider experience-oriented foods, like healthy recipes containing Maca and ginseng, which can improve the mood of the guests as well as their energy levels.

Breast health supplements

Iodine (Iodoral, containing potassium iodine and potassium iodide)

Enhance the methylation of estrones, an important concept in promoting breast health, with Di-indolemethane (a natural substance from cruciferous vegetables like broccoli), Trimethylglycine (TMG), Magnesium citrate. Magnesium is also important for decreasing anxiety, relaxing muscles and improving sleep and blood pressure.

Vitamin B12, vitamin B6, folate, Resveratrol, Omega 3 fatty acids, CoQ10 are all important for breast health, which is why Rhythmatix from Univera (vit B12, vit B6, folate, CoQ10, Resveratrol, fish oil EPA & DHA 2-4 capsules a day) should be renamed “breast –matix” because it supports both vessel and breast health.

Vitamin D3 supplementation is especially important in the Pacific Northwest where vitamin D deficiency is an epidemic. 25 hydroxy vit D levels above 75 nanograms/milliliter have been shown to have greater protection against breast cancer than lower levels of vitamin D.

Melatonin is an important neuropeptide for sleep and breast health.

The progestin new-to- nature synthetic drugs in birth control pills suppress the natural production of the woman’s own fertility-promoting hormone progesterone. Bio identical progesterone supplementation in deficient states to youthful levels, in a fashion that mimics youth, may help decrease some of the proliferative effects of those drugs. The cycling of progesterone often promotes periods of a decline in breast size that many women can see, feel, and measure.

Vitamin E– mixed tocopherols 400 iu po qd

Vitamin A retinyl palmitate

The healthy hormone adiponectin made by fat helps decrease the risk of breast cancer and heart disease. Enhance adiponectin production with exercise, vitamin E, specific phytonutrients from Cape aloe and other supplements that improve blood glucose control. I especially like the Univera product Level G (bananba, chromium nicotinate, vanadium, Cape Aloe, Aloe Qmatrix- aloe chromones, cinnamon) one tab taken twice to 4 times a day).

Avoid obesity and minimize inflammation. Supplement the diet with phytonutrients that address the underlying causes of inflammation, such as Scutellaria baicalensis, Acacia catechu, Turmeric/ curcumin -all of which are in the product from Univera called RegeniFREE.

Avoid sugar- use Xylitol instead, for its immune system enhancing effects as well as ability to sweeten foods, while contributing a lower blood glucose load.

STOP smoking.


  1. Curr Med Res Opin. 2008 Jan;24(1):139-49. Molecular basis of the potential of vitamin D to prevent cancer. Ingraham BA, Bragdon B, Nohe A. Source: University of Maine, Orono, ME 04469-5737, USA. bingraham@umche.maine.edu



Research strongly supports the view that efforts to improve vitamin D status would have significant protective effects against the development of cancer. The clinical research community is currently revising recommendations for optimal serum levels and for sensible levels of sun exposure, to levels greater than previously thought. Currently, most experts in the field believe that intakes of between 1000 and 4000 IU will lead to a more healthy level of serum 25(OH)D, at approximately 75 nmol/L that will offer significant protection effects against cancers of the breast, colon, prostate, ovary, lungs, and pancreas. The first randomized trial has shown significant protection against breast cancer, and other clinical trials will follow and ultimately lead to improved public health policies and significantly fewer cancers.

  1. J Pineal Res. 2011 Nov 7. doi: 10.1111/j.1600-079X.2011.00940.x. Melatonin interferes in the desmoplastic reaction in breast cancer by regulating cytokine production. Alvarez-García V, González A, Alonso-González C, Martínez-Campa C, Cos S. Source: Department of Physiology and Pharmacology, School of Medicine, University of Cantabria, Santander, Spain.


Melatonin exerts oncostatic effects on breast cancer by interfering with the estrogen signaling pathways. Melatonin inhibits aromatase enzyme in breast cancer cells and fibroblasts. …Lower levels of cytokines stimulate the differentiation of fibroblasts and decrease both aromatase activity and expression, thereby reducing the number of estrogen-producing cells proximal to malignant cells.

  1. Breast Cancer Res Treat. 2001 Jan;65(2):163-9. Effects of oral contraceptives on breast epithelial proliferation. Isaksson E, von Schoultz E, Odlind V, Söderqvist G, Csemiczky G, Carlström K, Skoog L, von Schoultz B. Source: Department of Oncology, Radiumhemmet, Karolinska Hospital, Stockholm, Sweden. erika@rah.ks.se


The association between oral contraceptive (OC) use and breast cancer is not fully understood. Estrogen is a known mitogen to breast epithelial cells, but there is still a controversy about the effect of added progestogens[progestins]. Fine needle aspiration (FNA) biopsies were used to assess epithelial proliferation in normal breast tissue from 106 healthy premenopausal women with and without oral contraceptives. In 26 women biopsies were performed before and after 2 months of OC use. Proliferation, expressed as percentage of Ki-67/MIB-1 positive cells, was correlated to endogenous progesterone, androgenic/anabolic compounds and exogenous progestogen[progestins]. We found a higher proliferation (p = 0.03) in OC users compared to non users, with mean values of 4.8% and 2.2%, respectively. There was a positive correlation between proliferation and progesterone levels in non-users and with serum levonorgestrel concentrations in women using OCs containing this progestogen (rs = 0.43, p = 0.02). Women using OCs had significantly lower serum androgen levels compared to naturally cycling women and free testosterone levels displayed an inverse relation to breast epithelial proliferation. There was a marked variation in the response to exogenous sex steroids. In certain women after 2 months of OC use, the percentage of MIB-1 positive cells was as high as 40-50%. The results add to the growing evidence that progestogens may be mitogenic in breast tissue. Increased proliferation during hormonal contraception should be regarded as an unwanted and potentially hazardous side effect. Efforts should be made to define hormonal contraceptive regimens which minimize breast epithelial proliferation and to identify those women with the most pronounced proliferative response.